SCHEMBL28944259

SCHEMBL28944259

CCCCCCN/C=C(\C(=O)O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.50
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
MLYCD O95822 1/20 0.43
FAAH O00519 7/20 0.42
CES1 P23141 5/20 0.42
CES2 O00748 3/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
S1PR1 P21453 4/20 0.39
S1PR3 Q99500 4/20 0.39
S1PR2 O95136 3/20 0.39
S1PR5 Q9H228 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28944281 0.81 EPHX1 (0.45) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL3285116 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL3284685 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL27828178 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL3279628 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL3284687 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL20598101 0.75 EP300 (0.60) FAAHCES1CES2MEN1CYP1A2
SCHEMBL3279622 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL3285120 0.75 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL7882683 0.74 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636762-B Method for synthesizing beta-trifluoromethyl enamine compound by catalyzing organic dye 江苏科技大学 2023-12-29 CN disclosed
CN-115636762-A Method for catalytically synthesizing beta-trifluoromethyl enamine compound by organic fuel 江苏科技大学 2023-01-24 CN disclosed