Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593039 | 0.82 | KDR (0.72) | KDR | |
| SCHEMBL5889204 | 0.79 | KDR (0.67) | KDR | |
| SCHEMBL5889270 | 0.79 | KDR (0.67) | KDR | |
| SCHEMBL5889166 | 0.77 | KDR (0.83) | KDR | |
| SCHEMBL5889168 | 0.76 | KDR (0.81) | KDR | |
| SCHEMBL5889065 | 0.75 | KDR (1.00) | KDR | |
| SCHEMBL5889029 | 0.74 | KDR (0.84) | KDR | |
| SCHEMBL6802594 | 0.74 | KDR (1.00) | KDR | |
| SCHEMBL5889043 | 0.74 | KDR (1.00) | KDR | |
| SCHEMBL7235060 | 0.72 | KDR (0.63) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687863-B | Amino-thiazolyl-pyrimidine derivatives and their use to treat cancer | ASTRAZENECA AB | 2012-09-12 | — | — | CN | disclosed |
| CN-101687863-A | Amino-thiazolyl-pyrimidine derivatives and their use to treat cancer | ASTRAZENECA AB | 2010-03-31 | — | — | CN | disclosed |