Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488194 | 0.82 | PIK3CA (0.61) | PIK3CANOD1KDM4ERXFP1LMNA | |
| SCHEMBL27858477 | 0.81 | PIK3CA (0.45) | PIK3CANOD1KDM4ERXFP1LMNA | |
| SCHEMBL27943426 | 0.72 | PIK3CA (0.44) | PIK3CANOD1KDM4ELMNAHTT | |
| 1,3-Dimethoxybenzene SCHEMBL27943423 | 0.72 | PIK3CA (0.52) | PIK3CANOD1KDM4EHTTMAPT | |
| SCHEMBL27924146 | 0.69 | PIK3CA (0.81) | PIK3CAKDM4ELMNAHTTTSHR | |
| SCHEMBL27858459 | 0.69 | PIK3CA (0.74) | PIK3CAKDM4ELMNAHTTKMT2A | |
| SCHEMBL27858622 | 0.69 | PIK3CA (0.80) | PIK3CAKDM4ELMNAHTTTSHR | |
| SCHEMBL27841038 | 0.67 | PIK3CA (0.65) | PIK3CAKDM4ERXFP1LMNAHTT | |
| SCHEMBL31315377 | 0.64 | AKR1B1 (0.47) | PIK3CANOD1KDM4ERXFP1LMNA | |
| SCHEMBL4015055 | 0.64 | KMT2A (0.61) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | disclosed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | disclosed |