Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 15/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.54 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800827 | 0.88 | PIK3CG (0.58) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL28800828 | 0.88 | PIK3CG (0.58) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL28946368 | 0.83 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL22246654 | 0.83 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL29808026 | 0.83 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL29808233 | 0.82 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL22246918 | 0.82 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL28800832 | 0.82 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL22230629 | 0.81 | PIK3CG (0.64) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL22230631 | 0.81 | PIK3CD (0.64) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721531-B | Novel liposome kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-07-29 | — | — | CN | disclosed |