Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213626 | 0.87 | POLB (0.40) | POLBMAPTKMT2AHRH3BCHE | |
| SCHEMBL28802697 | 0.86 | TLR7 (0.38) | KMT2AHRH3CYP2D6 | |
| SCHEMBL28802701 | 0.85 | TLR7 (0.43) | MAPTCYP2D6 | |
| SCHEMBL28802649 | 0.85 | TLR7 (0.37) | HRH3CYP2D6 | |
| SCHEMBL24733112 | 0.84 | POLB (0.36) | POLBMAPTKMT2AHRH3BCHE | |
| SCHEMBL30947337 | 0.84 | POLB (0.36) | POLBMAPTKMT2AHRH3BCHE | |
| SCHEMBL28802613 | 0.82 | TLR7 (0.41) | KMT2A | |
| SCHEMBL28802651 | 0.80 | USP2 (0.38) | MAPTCYP2D6 | |
| SCHEMBL28802743 | 0.79 | USP2 (0.37) | MAPTCYP2D6 | |
| SCHEMBL29756236 | 0.75 | HRH3 (0.41) | POLBMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736210-A | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |