Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930609 | 0.93 | MAPT (0.37) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL23930498 | 0.93 | MAPT (0.38) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL30210848 | 0.93 | MAPT (0.38) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL23930488 | 0.89 | MAPT (0.36) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL30210925 | 0.89 | MAPT (0.36) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL25199172 | 0.88 | SMN1; SMN2 (0.38) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL31411943 | 0.88 | SMN1; SMN2 (0.38) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL23930462 | 0.87 | NPC1 (0.42) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL31633436 | 0.87 | CCNA2 (0.37) | MAPTMEN1KMT2APOLBCDK5 | |
| SCHEMBL23930595 | 0.87 | CCNA2 (0.37) | MAPTMEN1KMT2APOLBCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697979-A | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2023-02-03 | — | — | CN | claimed |