Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 18/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920799 | 0.89 | PTPRB (0.80) | PTPRB | |
| SCHEMBL679472 | 0.89 | PTPRB (0.80) | PTPRBPTPN1 | |
| SCHEMBL679471 | 0.89 | PTPRB (0.80) | PTPRBPTPN1 | |
| SCHEMBL28828130 | 0.87 | PTPRB (0.65) | PTPRBPTPN1 | |
| SCHEMBL24309003 | 0.79 | PTPRB (0.83) | PTPRB | |
| SCHEMBL468266 | 0.78 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468270 | 0.78 | PTPRB (1.00) | PTPRB | |
| SCHEMBL20060124 | 0.77 | PTPRB (0.83) | PTPRB | |
| SCHEMBL27939325 | 0.77 | PTPRB (0.60) | PTPRBPTPN1 | |
| SCHEMBL27920739 | 0.76 | PTPRB (0.75) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347565-A | Compositions and methods for treating ocular edema, neovascularization, and related diseases | AKEBIA THERAPEUTICS INC | 2013-10-09 | — | — | CN | claimed |
| CN-103347565-A | Compositions and methods for treating ocular edema, neovascularization, and related diseases | AKEBIA THERAPEUTICS INC | 2013-10-09 | — | — | CN | disclosed |