SCHEMBL28947892

SCHEMBL28947892

CC1=Cc2c(-c3ccccc3)cccc2C1(I)I

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
AKT1 P31749 1/20 0.33
AKT2 P31751 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP2A6 P11509 2/20 0.32
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2B6 P20813 1/20 0.32
ALDH1A1 P00352 3/20 0.31
HSD17B10 Q99714 2/20 0.31
HPGD P15428 1/20 0.31
BCL2L1 Q07817 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LIMK1 P53667 2/20 0.31
CLK4 Q9HAZ1 2/20 0.31
PLK4 O00444 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28815102 0.79 PDCD1 (0.36) PDCD1CD274AKT1AKT2SLC6A2
SCHEMBL27551823 0.79 PDCD1 (0.36) PDCD1CD274AKT1AKT2SLC6A2
SCHEMBL27627844 0.78 PDCD1 (0.35) PDCD1CD274SLC6A2SLC6A4SLC6A3
SCHEMBL27519768 0.78 PDCD1 (0.35) PDCD1CD274SLC6A2SLC6A4SLC6A3
SCHEMBL5273392 0.78 PDCD1 (0.35) PDCD1CD274SLC6A2SLC6A4SLC6A3
SCHEMBL28179764 0.77 PDCD1 (0.34) PDCD1CD274SLC6A2SLC6A4SLC6A3
SCHEMBL218743 0.74 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL5616230 0.74 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL217235 0.74 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL217522 0.74 PDCD1 (0.36) PDCD1CD274CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454389-B Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin DL化学株式会社 2022-07-15 CN disclosed
CN-111454389-A Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin 大林产业株式会社 2020-07-28 CN disclosed