Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.34 |
| ▸ | HTR2C | P28335 | 8/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SOD3 | P08294 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996760 | 0.82 | HTR2C (0.36) | HTR2AHTR2CHTR2BSOD3 | |
| SCHEMBL24731148 | 0.79 | HTR2A (0.36) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1991346 | 0.78 | HTR2A (0.35) | HTR2AHTR2C | |
| SCHEMBL29221929 | 0.76 | HTR2A (0.34) | HTR2AHTR2C | |
| SCHEMBL21131004 | 0.74 | SSTR4 (0.39) | — | |
| SCHEMBL1290603 | 0.74 | SSTR4 (0.33) | HTR2AHTR2C | |
| SCHEMBL1991347 | 0.73 | SSTR4 (0.36) | HTR2AHTR2C | |
| SCHEMBL2002227 | 0.73 | HTR2C (0.39) | HTR2AHTR2CSOD3 | |
| SCHEMBL1709933 | 0.73 | KDM4E (0.44) | — | |
| Hydrochloric Acid SCHEMBL5779163 | 0.72 | SSTR4 (0.35) | HTR2AHTR2CSOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677729-A | AAK1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |