Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560306 | 0.86 | AAK1 (0.55) | PRMT5WDR77AAK1PCSK9USP30 | |
| SCHEMBL2553319 | 0.86 | AAK1 (0.55) | PRMT5WDR77AAK1PCSK9USP30 | |
| SCHEMBL1141513 | 0.86 | AAK1 (0.55) | PRMT5WDR77AAK1PCSK9USP30 | |
| SCHEMBL17606846 | 0.84 | PRMT5 (0.46) | PRMT5WDR77AAK1USP30LIPG | |
| SCHEMBL5106947 | 0.83 | AAK1 (0.48) | PRMT5WDR77AAK1USP30LIPG | |
| SCHEMBL14014450 | 0.83 | AAK1 (0.48) | PRMT5WDR77AAK1USP30LIPG | |
| SCHEMBL12020859 | 0.83 | AAK1 (0.48) | PRMT5WDR77AAK1USP30LIPG | |
| SCHEMBL5106944 | 0.83 | AAK1 (0.48) | PRMT5WDR77AAK1USP30LIPG | |
| SCHEMBL28817169 | 0.82 | AAK1 (0.42) | PRMT5WDR77AAK1PCSK9USP30 | |
| SCHEMBL15092669 | 0.81 | PRMT5 (0.49) | PRMT5WDR77AAK1PCSK9USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |