Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531590 | 0.93 | NR1H4 (0.69) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL29880943 | 0.91 | NR1H4 (0.77) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL689187 | 0.91 | NR1H4 (0.77) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL272855 | 0.83 | NR1H4 (0.68) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL688528 | 0.81 | NR1H4 (0.76) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL6531592 | 0.81 | NR1H4 (0.72) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL28819542 | 0.81 | NR1H4 (0.43) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL4298714 | 0.80 | NR1H4 (0.66) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL28948679 | 0.80 | NR1H4 (0.70) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL274595 | 0.80 | NR1H4 (1.00) | NR1H4ESR1NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |