⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708489 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL10715341 | 0.67 | — | — | |
| SCHEMBL2143209 | 0.67 | — | — | |
| SCHEMBL8667227 | 0.66 | TSHR (0.32) | — | |
| SCHEMBL11061205 | 0.65 | — | — | |
| SCHEMBL28160009 | 0.64 | — | — | |
| SCHEMBL8076492 | 0.64 | — | — | |
| SCHEMBL8076493 | 0.64 | — | — | |
| SCHEMBL627386 | 0.63 | — | — | |
| SCHEMBL27468585 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805218-B | Preparation method of rosuvastatin calcium intermediate | 重庆普佑生物医药有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-114805218-A | Preparation method of rosuvastatin calcium intermediate | 法姆瑞斯医药科技(北京)有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114805218-B | Preparation method of rosuvastatin calcium intermediate | 重庆普佑生物医药有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114805218-B | Preparation method of rosuvastatin calcium intermediate | 重庆普佑生物医药有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114805218-A | Preparation method of rosuvastatin calcium intermediate | 法姆瑞斯医药科技(北京)有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805218-A | Preparation method of rosuvastatin calcium intermediate | 法姆瑞斯医药科技(北京)有限公司 | 2022-07-29 | — | — | CN | disclosed |