Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.55 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448975 | 0.86 | PTGER4 (0.62) | PTGER4SCN8ASCN10APTGER2LMNA | |
| SCHEMBL28949682 | 0.84 | CYP1A2 (0.54) | PTGER4LMNAL3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL4449413 | 0.82 | PTGER4 (0.57) | PTGER4SCN8ASCN10APTGER2LMNA | |
| SCHEMBL28949721 | 0.80 | PTGER4 (0.53) | PTGER4SCN8ASCN10APTGER2LMNA | |
| SCHEMBL11575054 | 0.77 | SCN8A (0.56) | PTGER4SCN8ASCN10APTGER2LMNA | |
| SCHEMBL19524135 | 0.76 | SCN8A (0.58) | PTGER4SCN8ASCN10APTGER2LMNA | |
| SCHEMBL7182380 | 0.76 | TTR (0.58) | PTGER4SCN8ASCN10ALMNAL3MBTL1 | |
| SCHEMBL11577659 | 0.76 | GAA (0.54) | PTGER4PTGER2L3MBTL1SMN1; SMN2PNLIP | |
| SCHEMBL7861651 | 0.74 | KMT2A (0.55) | SCN8ASCN10ASMN1; SMN2PNLIPHTR2A | |
| SCHEMBL5363227 | 0.74 | EPAS1 (0.60) | PTGER4SCN8ASCN10APTGER2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698292-A | Aptamers binding to thiamine analogs and derivatives | 梅里特斯英国第二有限公司 | 2023-02-03 | — | — | CN | disclosed |