SCHEMBL28950833

SCHEMBL28950833

CC1(Br)c2ccccc2Cc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.59
HTR2C P28335 2/20 0.44
DRD2 P14416 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HRH1 P35367 2/20 0.39
HTR2B P41595 1/20 0.39
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38
DRD3 P35462 1/20 0.38
KDM1A O60341 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27887642 0.84 HTR2A (0.52) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL8816862 0.82 HTR2A (0.61) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL29901667 0.82 HTR2A (0.61) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL30843843 0.80 HTR2A (0.59) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL13672458 0.78 HTR2A (0.57) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL26798934 0.77 HTR2A (0.50) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL20143949 0.76 HTR2A (0.55) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL22068590 0.75 HTR2A (0.53) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL18678855 0.75 HTR2A (0.53) HTR2AHTR2CDRD2SLC6A2SLC6A4
SCHEMBL4517706 0.73 HTR2A (0.52) HTR2AHTR2CDRD2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264856-B Sulfonium salt, photoacid generator, and photosensitive composition 东京应化工业株式会社 2022-11-22 CN disclosed