Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952086 | 1.00 | HCRTR1 (0.46) | HCRTR1HCRTR2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL28834010 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2KDM4EALDH1A1HTT | |
| SCHEMBL28834009 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2KDM4EALDH1A1HTT | |
| SCHEMBL28834040 | 0.84 | MCHR1 (0.42) | HCRTR1HCRTR2MCHR1ALDH1A1 | |
| SCHEMBL28834042 | 0.84 | MCHR1 (0.42) | HCRTR1HCRTR2MCHR1ALDH1A1 | |
| SCHEMBL28834277 | 0.81 | PDE3B (0.44) | HCRTR1HCRTR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28834279 | 0.81 | PDE3B (0.44) | HCRTR1HCRTR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL23378741 | 0.81 | HCRTR1 (0.52) | HCRTR1HCRTR2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL28834179 | 0.79 | HCRTR2 (0.47) | HCRTR1HCRTR2SMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL28834180 | 0.79 | HCRTR2 (0.47) | HCRTR1HCRTR2SMN1; SMN2ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |