Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 7/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276037 | 1.00 | PIK3CD (0.51) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL28952681 | 0.88 | PIK3CD (0.49) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL30276072 | 0.88 | PIK3CD (0.49) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL18038546 | 0.88 | PIK3CD (0.51) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL30276043 | 0.88 | PIK3CD (0.51) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL28964731 | 0.88 | PIK3CD (0.51) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL14736652 | 0.88 | PIK3CD (0.51) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL14736487 | 0.85 | PIK3CD (0.53) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL30276021 | 0.80 | PIK3CD (0.62) | PIK3CDKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL28952539 | 0.80 | PIK3CD (0.62) | PIK3CDKCNH2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703770-A | Pyrimidinamine compound and composition and application thereof | 深圳范恩柯尔精准医疗有限公司 | 2023-02-17 | — | — | CN | disclosed |