SCHEMBL28952251

SCHEMBL28952251

Cc1cc(-n2nc3c(c2-n2cc[nH]c2=O)C(C)N(C(=O)O)CC3)cc(C)c1F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21175410 1.00 GLP1R (0.38) GLP1R
SCHEMBL21175263 0.91 GLP1R (0.38) GLP1R
SCHEMBL21175150 0.91 GLP1R (0.35) GLP1R
SCHEMBL26122776 0.88 GLP1R (0.36) GLP1R
SCHEMBL31692385 0.83 GLP1R (0.34) GLP1R
SCHEMBL38651890 0.83 GLP1R (0.35) GLP1R
SCHEMBL38652284 0.81 GLP1R (0.35) GLP1R
SCHEMBL20014766 0.80 — —
SCHEMBL21183679 0.80 GLP1R (0.36) GLP1R
SCHEMBL21175426 0.79 GLP1R (0.35) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115698003-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2023-02-03 — — CN disclosed
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