Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 20/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 19/20 | 0.58 |
| ▸ | CLK2 | P49760 | 18/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 18/20 | 0.58 |
| ▸ | DYRK2 | Q92630 | 18/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 18/20 | 0.58 |
| ▸ | DYRK3 | O43781 | 17/20 | 0.58 |
| ▸ | CLK3 | P49761 | 15/20 | 0.58 |
| ▸ | DYRK4 | Q9NR20 | 14/20 | 0.58 |
| ▸ | GSK3B | P49841 | 11/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899856 | 1.00 | CLK1 (0.58) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL28953207 | 1.00 | CLK1 (0.58) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL28842957 | 0.95 | CLK1 (0.59) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL23510756 | 0.95 | CLK1 (0.59) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL29899977 | 0.95 | CLK1 (0.59) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL28842989 | 0.86 | CLK1 (0.60) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL23510736 | 0.86 | CLK1 (0.60) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL29899822 | 0.86 | CLK1 (0.60) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL23510768 | 0.84 | CLK1 (0.50) | CLK1CLK4CLK2DYRK1ADYRK2 | |
| SCHEMBL28843139 | 0.84 | CLK1 (0.50) | CLK1CLK4CLK2DYRK1ADYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929690-B | Novel heterocyclic derivatives having cardiomyocyte proliferative activity for the treatment of heart disease | 同济大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-114929690-A | Novel heterocyclic derivatives with cardiomyocyte proliferative activity for the treatment of cardiac diseases | 同济大学 | 2022-08-19 | — | — | CN | disclosed |