⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026910 | 0.78 | — | — | |
| SCHEMBL29024602 | 0.76 | — | — | |
| SCHEMBL6708557 | 0.75 | — | — | |
| SCHEMBL4308432 | 0.72 | — | — | |
| SCHEMBL29228141 | 0.72 | — | — | |
| SCHEMBL28196707 | 0.72 | — | — | |
| SCHEMBL29198299 | 0.72 | — | — | |
| SCHEMBL17065248 | 0.70 | — | — | |
| SCHEMBL29642086 | 0.70 | — | — | |
| SCHEMBL30310796 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874353-B | Microbiocidal derivatives | 先正达农作物保护股份公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114276362-B | Use of IGF-1R small molecule inhibitors in the preparation of combination drugs for the treatment and/or prevention of cancer | 杭州拿因生物科技有限责任公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114315848-B | Small molecule inhibitors of insulin-like growth factor-1 receptor and uses thereof | 杭州拿因生物科技有限责任公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-110669054-B | Insulin-like growth factor-1 receptor tyrosine kinase inhibitors and uses thereof | 南京药石科技股份有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114315848-A | Small molecule inhibitors of insulin-like growth factor-1receptor and uses thereof | 浙江大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114276362-A | Application of IGF-1R small molecule inhibitor in preparation of combined medicine for treating and/or preventing cancer | 浙江大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-107004906-A | Magnesium-containing electrolyte | 和光纯药工业株式会社 | 2017-08-01 | — | — | CN | disclosed |