Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.76 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | LYN | P07948 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | TEC | P42680 | 2/20 | 0.44 |
| ▸ | TXK | P42681 | 2/20 | 0.44 |
| ▸ | BMX | P51813 | 2/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151010 | 0.86 | BTK (1.00) | BTKJAK2LCKLYNKIT | |
| SCHEMBL123628 | 0.86 | BTK (1.00) | BTKJAK2LCKLYNKIT | |
| SCHEMBL150448 | 0.81 | BTK (0.68) | BTKJAK2LCKLYNKIT | |
| SCHEMBL148716 | 0.80 | BTK (0.88) | BTKJAK2LCKLYNKIT | |
| SCHEMBL27982076 | 0.78 | BTK (0.83) | BTKJAK2LCKLYNKIT | |
| SCHEMBL123138 | 0.74 | BTK (0.77) | BTKJAK2LCKLYNKIT | |
| SCHEMBL148551 | 0.74 | BTK (0.78) | BTKJAK2LCKLYNKIT | |
| SCHEMBL122327 | 0.74 | BTK (0.78) | BTKJAK2LCKLYNKIT | |
| SCHEMBL145050 | 0.73 | BTK (0.75) | BTKJAK2LCKLYNKIT | |
| SCHEMBL123856 | 0.73 | BTK (0.75) | BTKJAK2LCKLYNKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074804-A | Carbazole derivates | 百时美施贵宝公司 | 2017-08-18 | — | — | CN | disclosed |