Fenamidone

Fenamidone

SCHEMBL28954496

CSC1=N[C@@](C)(c2ccccc2)C(=O)N1Nc1ccccc1.ONc1ccccc1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 3/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
CCR6 P51684 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CASP6 P55212 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
BACE1 P56817 2/20 0.30
REN P00797 1/20 0.30
APP P05067 1/20 0.30
BACE2 Q9Y5Z0 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenamidone SCHEMBL22306 0.94 CYP1A2 (0.38) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL550975 0.94 CYP1A2 (0.38) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL15286728 0.94 CYP1A2 (0.38) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL17701153 0.92 CYP1A2 (0.37) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL27841614 0.92 CYP1A2 (0.37) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL17701150 0.91 CYP1A2 (0.35) CYP1A2ALDH1A1GAAMAPTHPGD
Fenamidone SCHEMBL28214387 0.89 CYP1A2 (0.38) CYP1A2ALDH1A1GAAMAPTHPGD
SCHEMBL9232334 0.88 GAA (0.34) CYP1A2ALDH1A1GAAMAPTHPGD
SCHEMBL9232757 0.86 MAPT (0.36) CYP1A2ALDH1A1GAAMAPTHPGD
SCHEMBL9234117 0.86 MAPT (0.36) CYP1A2ALDH1A1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105123695-B Soft rot control agent and Disease-Control for Soft-Rotting method 石原产业株式会社 2018-03-06 CN disclosed