Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959102 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL15485147 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL3356780 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL4556222 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL4959489 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL4960570 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL55659 | 0.98 | KMT2A (0.55) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| Methane SCHEMBL2213416 | 0.96 | KMT2A (0.53) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL9181335 | 0.96 | KMT2A (0.53) | KMT2AMEN1NUDT1BACE1HSP90AA1 | |
| SCHEMBL42554 | 0.96 | KMT2A (0.57) | KMT2AMEN1NUDT1BACE1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105618141-B | Utilize the preparation method of resin-carried chirality Salen-Co (III) catalyst of Merrifield | 吉林化工学院 | 2018-07-06 | — | — | CN | claimed |