SCHEMBL28957134

SCHEMBL28957134

O=C1NCCC(c2ccc(F)cc2)O1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 14/20 0.42
FADS1 O60427 5/20 0.41
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28957132 1.00 MAOB (0.42) MAOBFADS1TDP1
SCHEMBL3650411 0.83 DDB1 (0.41) TDP1
SCHEMBL2893585 0.82 MAOB (0.44) MAOBFADS1TDP1
SCHEMBL13950143 0.82 MAOB (0.42) MAOB
SCHEMBL1705219 0.82 MAOB (0.42) MAOB
SCHEMBL5021254 0.82 MAOB (0.44) MAOBFADS1TDP1
SCHEMBL14521456 0.82 MAOB (0.42) MAOB
SCHEMBL31410633 0.82 KDM1A (0.38) MAOB
SCHEMBL31410548 0.79 SLC6A2 (0.39)
SCHEMBL31322250 0.77 MAOB (0.37) MAOBFADS1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076017-A1 CARBAMATES FOR USE AS SARM1 INHIBITORS GENENTECH, INC. (US) 2025-04-10 WO disclosed
CN-114605272-B Preparation method of (R) -fluoxetine and derivatives thereof 中国科学技术大学 2023-09-08 CN disclosed
CN-114605272-A Preparation method of (R) -fluoxetine and derivative thereof 中国科学技术大学 2022-06-10 CN disclosed