Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178009 | 0.89 | KMT2A (1.00) | KMT2ATNKS2PARP1KDM4ELMNA | |
| SCHEMBL31716910 | 0.85 | KMT2A (0.80) | KMT2ATNKS2PARP1TNKSKDM4E | |
| SCHEMBL259477 | 0.84 | KMT2A (0.68) | KMT2APARP1KDM4EMAPTGAA | |
| SCHEMBL7978349 | 0.82 | KMT2A (0.74) | KMT2ATNKS2PARP1KDM4ELMNA | |
| SCHEMBL4099549 | 0.82 | KMT2A (0.74) | KMT2ATNKS2PARP1TNKSKDM4E | |
| SCHEMBL31716237 | 0.81 | KMT2A (0.72) | KMT2ATNKS2PARP1KDM4ELMNA | |
| SCHEMBL31716658 | 0.80 | KMT2A (0.67) | KMT2ATNKS2PARP1GUSBKDM4E | |
| SCHEMBL3518718 | 0.80 | KMT2A (0.67) | KMT2ATNKS2PARP1TNKSKDM4E | |
| SCHEMBL8649616 | 0.80 | PARP1 (0.59) | KMT2ATNKS2PARP1TNKSGUSB | |
| SCHEMBL3320433 | 0.78 | GAA (0.75) | LMNAMAPTRAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115716806-A | Synthetic method of 2- (4-hydroxybenzyl) -4 (3H) -quinazolinone | 南方海洋科学与工程广东省实验室(湛江) | 2023-02-28 | — | — | CN | claimed |
| CN-115716806-A | Synthetic method of 2- (4-hydroxybenzyl) -4 (3H) -quinazolinone | 南方海洋科学与工程广东省实验室(湛江) | 2023-02-28 | — | — | CN | disclosed |
| CN-115716806-A | Synthetic method of 2- (4-hydroxybenzyl) -4 (3H) -quinazolinone | 南方海洋科学与工程广东省实验室(湛江) | 2023-02-28 | — | — | CN | disclosed |
| CN-115716806-A | Synthetic method of 2- (4-hydroxybenzyl) -4 (3H) -quinazolinone | 南方海洋科学与工程广东省实验室(湛江) | 2023-02-28 | — | — | CN | disclosed |