Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267711 | 0.88 | MEN1 (0.58) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8569494 | 0.87 | MEN1 (0.56) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL2443270 | 0.86 | MEN1 (0.71) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL38662586 | 0.86 | MEN1 (0.71) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8574356 | 0.86 | HSD17B10 (0.55) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8569908 | 0.86 | KDM4E (0.55) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28342069 | 0.83 | KDM4E (0.54) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL21878637 | 0.79 | MEN1 (0.75) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL8170480 | 0.78 | MEN1 (0.73) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28129469 | 0.78 | MEN1 (0.60) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557888-B | Method for preparing quinoline derivative by photocatalysis of N-aryl glycinate | 安徽理工大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-115557888-A | Method for preparing quinoline derivative by photocatalysis of N-aryl glycine ester | 安徽理工大学 | 2023-01-03 | — | — | CN | disclosed |