Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196924 | 0.90 | TDP1 (0.62) | TDP1VNN1ATML3MBTL1KMT2A | |
| SCHEMBL29875565 | 0.90 | TDP1 (0.62) | TDP1VNN1ATML3MBTL1KMT2A | |
| SCHEMBL28879925 | 0.89 | TDP1 (0.53) | TDP1VNN1ATMHPRT1L3MBTL1 | |
| SCHEMBL28630441 | 0.82 | TDP1 (0.56) | TDP1ATMHPRT1L3MBTL1KMT2A | |
| SCHEMBL10628907 | 0.80 | TDP1 (0.79) | TDP1ATMHPRT1L3MBTL1KMT2A | |
| SCHEMBL27784108 | 0.80 | TDP1 (0.79) | TDP1ATMHPRT1L3MBTL1KMT2A | |
| SCHEMBL1781872 | 0.80 | TDP1 (0.58) | TDP1ATMHPRT1L3MBTL1KMT2A | |
| SCHEMBL29972613 | 0.79 | HPRT1 (0.58) | TDP1ATMHPRT1HPGDALDH1A1 | |
| SCHEMBL574431 | 0.79 | HPRT1 (0.58) | TDP1ATMHPRT1HPGDALDH1A1 | |
| SCHEMBL2528231 | 0.79 | HPRT1 (0.58) | TDP1ATMHPRT1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |