Urea

Urea

SCHEMBL28958224

N=C(N)NOP(=O)(O)O.NC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.40
TDP1 Q9NUW8 2/20 0.30
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27438 0.95
Phosphine SCHEMBL5594612 0.92 CA4 (0.36) CA4TDP1FDPSBLM
SCHEMBL11663057 0.92 CA4 (0.42) CA4TDP1FDPSBLM
Hydrochloric Acid SCHEMBL1803055 0.92 CA4 (0.36) CA4TDP1FDPSBLM
SCHEMBL17061103 0.92 CA4 (0.36) CA4TDP1FDPSBLM
Water SCHEMBL11657672 0.90 CA4 (0.40) CA4TDP1FDPSBLM
Water SCHEMBL17061109 0.90 CA4 (0.40) CA4TDP1FDPSBLM
SCHEMBL27494032 0.81
Guanidine SCHEMBL28362043 0.80 CA4 (0.40) CA4TDP1FDPSBLMLMNA
SCHEMBL4948771 0.79 CA4 (0.32) CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115584059-A Preparation and application of intumescent halogen-free flame retardant 福州大学 2023-01-10 CN disclosed