Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Salicyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyl Alcohol SCHEMBL29453973 | 0.97 | — | — | |
| Salicyl Alcohol SCHEMBL17028795 | 0.97 | HSPA5 (0.65) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL15639 | 0.97 | — | — | |
| Salicyl Alcohol SCHEMBL10793667 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL11408121 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL29682418 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL31186654 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL886904 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL20659833 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 | |
| Salicyl Alcohol SCHEMBL3154776 | 0.94 | HSPA5 (0.62) | HSPA5HIF1ATSHRCYP2D6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289697-B | Scoring balloon with translating score line | 巴德股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-114795402-A | Scoring balloon with translating score line | 巴德股份有限公司 | 2022-07-29 | — | — | CN | disclosed |