SCHEMBL28958365

SCHEMBL28958365

C=C(C)C(=O)OC(C)CCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCCC(C)OC(=O)C(=C)C)cc3)c(C)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 3/20 0.38
KMT2A Q03164 2/20 0.38
MAPK1 P28482 2/20 0.38
PPARG P37231 9/20 0.38
PPARD Q03181 9/20 0.38
PPARA Q07869 8/20 0.38
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958531 0.87 MAPT (0.41) POLBTDP1APEX1HTTMAPT
SCHEMBL29039778 0.86 PPARG (0.37) POLBTDP1APEX1HTTMAPT
SCHEMBL31077987 0.85 MAPT (0.38) TDP1MAPTKMT2AMAPK1PPARG
SCHEMBL21839828 0.85 MAPT (0.38) TDP1MAPTKMT2AMAPK1PPARG
SCHEMBL28958369 0.85 PPARG (0.37) POLBTDP1APEX1HTTMAPK1
SCHEMBL13874313 0.84 KMT2A (0.43) TDP1MAPTKMT2AMAPK1PPARG
SCHEMBL13874312 0.84 MAPT (0.43) TDP1MAPTKMT2AMAPK1PPARG
SCHEMBL9108184 0.84 TDP1 (0.51) POLBTDP1APEX1HTTMAPT
SCHEMBL19978522 0.83 POLB (0.59) POLBTDP1APEX1HTTMAPT
SCHEMBL17301279 0.83 TDP1 (0.50) POLBTDP1APEX1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN claimed
CN-118344882-A Method for improving stretchability of liquid crystal composition, liquid crystal composition and optical film 上海先幻高科新材料有限公司 2024-07-16 CN disclosed
CN-115368912-B Liquid crystal composition, reflective film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2024-05-14 CN disclosed
CN-115322796-B Liquid crystal composition, moth eye mask and preparation method of moth eye mask 上海先认新材料合伙企业(有限合伙) 2024-05-10 CN disclosed
CN-115301082-B Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2024-01-16 CN disclosed
CN-116875324-A Liquid crystal composition, liquid crystal transfer film and preparation method of liquid crystal transfer film 上海先认新材料合伙企业(有限合伙) 2023-10-13 CN disclosed
CN-115368912-A Liquid crystal composition, reflective film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-22 CN disclosed
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN disclosed
CN-115301082-A Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2022-11-08 CN disclosed