SCHEMBL28958555

SCHEMBL28958555

Nc1ccc2ccccc2c1B(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 5/20 0.46
TSHR P16473 2/20 0.46
HPGD P15428 2/20 0.46
CYP3A4 P08684 1/20 0.46
KEAP1 Q14145 1/20 0.46
CYP2A6 P11509 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPRT1 P00492 2/20 0.44
PTPN22 Q9Y2R2 1/20 0.39
HDAC3 O15379 1/20 0.39
IDO1 P14902 1/20 0.39
EP300 Q09472 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT8 Q9H7Z6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12734305 0.77 PTPN22 (0.56) ALDH1A1HSD17B10TSHRHPGDCYP2A6
SCHEMBL29952231 0.77 PTPN22 (0.56) ALDH1A1HSD17B10TSHRHPGDCYP2A6
SCHEMBL5432699 0.77 CYP2A6 (0.46) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL29993985 0.75 POLB (0.45) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL5773829 0.75 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL29234084 0.75 CYP2A6 (0.54) ALDH1A1HSD17B10TSHRCYP3A4CYP2A6
SCHEMBL2151120 0.75 TSHR (0.54) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL22584748 0.75 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL20984005 0.75 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL29950886 0.75 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304493-A Compound and application thereof 北京鼎材科技有限公司 2022-11-08 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed