Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610244 | 0.87 | KDM4E (0.51) | HTR7KDM4EMAPK1TP53RAB9A | |
| SCHEMBL29997368 | 0.87 | KDM4E (0.51) | HTR7KDM4EMAPK1TP53RAB9A | |
| SCHEMBL11023081 | 0.84 | TP53 (0.65) | HTR7KDM4EMAPK1TP53RAB9A | |
| SCHEMBL30668196 | 0.83 | HTR1B (0.46) | KDM4EMAPK1RAB9ACD274LMNA | |
| SCHEMBL28960000 | 0.83 | HTR1B (0.46) | KDM4EMAPK1RAB9ACD274LMNA | |
| SCHEMBL10677209 | 0.81 | TP53 (0.49) | HTR7KDM4EMAPK1TP53RAB9A | |
| SCHEMBL29997360 | 0.81 | PDCD1 (0.50) | HTR7KDM4EMAPK1TP53RAB9A | |
| SCHEMBL30394059 | 0.80 | CD274 (0.39) | KDM4EMAPK1TP53RAB9ACD274 | |
| SCHEMBL19897916 | 0.80 | CD274 (0.39) | KDM4EMAPK1TP53RAB9ACD274 | |
| SCHEMBL9482701 | 0.79 | TP53 (0.62) | HTR7KDM4EMAPK1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |