SCHEMBL28961111

SCHEMBL28961111

[N-]=[N+]=NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.51
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
TDO2 P48775 1/20 0.46
IDO2 Q6ZQW0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199308 0.87 IDO1 (0.52) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL30141305 0.86 IDO1 (0.67) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL20090679 0.86 IDO1 (0.67) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL28746381 0.85 IDO1 (0.48) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL28400232 0.85 IDO1 (0.40) IDO1
Ammonia Solution, Strong SCHEMBL28327420 0.85 IDO1 (0.50) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL20653587 0.85 IDO1 (0.54) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL23066851 0.84 IDO1 (0.55) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL20090569 0.84 IDO1 (0.55) IDO1CYP3A4CYP2C9TDO2IDO2
SCHEMBL20199084 0.84 IDO1 (0.50) IDO1CYP3A4CYP2C9TDO2IDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745982-B Oxadiazole compound and preparation method and application thereof 中国药科大学 2024-09-17 CN disclosed
CN-115745982-A Oxadiazole compound and preparation method and application thereof 中国药科大学 2023-03-07 CN disclosed