SCHEMBL2896229

SCHEMBL2896229

COC(=O)C(C)C.[SnH4]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66536 0.97
SCHEMBL846523 0.97 SMN1; SMN2 (0.52)
SCHEMBL2204588 0.93
SCHEMBL22401459 0.93
Hydrochloric Acid SCHEMBL6942925 0.93
SCHEMBL8655368 0.93
Ammonia Solution, Strong SCHEMBL4405501 0.93
SCHEMBL22832217 0.93
Methyl Alcohol SCHEMBL8750993 0.93
SCHEMBL5820792 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000879-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONIC ACID ESTERS BAYER AG (DE) 1980-08-20 EP claimed
EP-3450436-B1 CONDENSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2022-07-27 EP disclosed
US-11390634-B2 Fused heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-07-19 US disclosed
US-20210115067-A1 FUSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-22 US disclosed
US-10981934-B2 Fused heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-20 US disclosed
US-20200140462-A1 FUSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-05-07 US disclosed
US-10577382-B2 Fused heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-03-03 US disclosed
US-20190106437-A1 FUSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-04-11 US disclosed
US-7662846-B2 Selective spirocyclic glucocorticoid receptor modulators MERCK SHARP & DOHME CORP. (US) 2010-02-16 US disclosed
EP-1617806-B1 SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS MERCK & CO INC (US) 2009-11-04 EP disclosed
EP-1617806-A4 SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS MERCK & CO INC (US) 2006-11-02 EP disclosed
US-20060217563-A1 Selective spirocyclic glucocorticoid receptor modulators MERCK SHARP & DOHME CORP. 2006-09-28 US disclosed
EP-1617806-A2 SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS Merck & Co., Inc. (US) 2006-01-25 EP disclosed
WO-2004093805-A2 SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS MERCK & CO., INC. (US) 2004-11-04 WO disclosed
US-4542192-A Reactive hardenable polymer mixture and process for the preparation of hardened products therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-17 US disclosed
US-4252737-A Process for the production of aromatic carbonic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4208488-A POLYESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed
US-4176143-A MIXTURE WITH ONE OR MORE POLYMERS HAVING HYDROXYL GROUPS AND/OR 1,2-EPOXY GROUPS, COATINGS HOECHST AKTIENGESELLSCHAFT (DE) 1979-11-27 US disclosed