Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | XIAP | P98170 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962431 | 0.83 | MEN1 (0.76) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL4961093 | 0.83 | KMT2A (0.67) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL28931485 | 0.80 | MEN1 (0.71) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL4959942 | 0.80 | KMT2A (0.63) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL28962671 | 0.80 | XIAP (0.59) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL17933317 | 0.80 | XIAP (0.58) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL28931501 | 0.79 | XIAP (0.58) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL28931495 | 0.79 | MEN1 (0.69) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL14020311 | 0.78 | KMT2A (0.50) | MEN1KMT2APOLBXIAPMAPT | |
| SCHEMBL16705684 | 0.76 | XIAP (0.58) | MEN1KMT2APOLBXIAPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417833-B | Synthesis method of 2-amido naphtho [1,2-d ] thiazole | 池州学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115417833-A | Synthesis method of 2-acylamino naphtho [1,2-d ] thiazole | 池州学院 | 2022-12-02 | — | — | CN | disclosed |