SCHEMBL28964247

SCHEMBL28964247

C=C(C)C(=O)OC(C)NCCl

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246672 0.82 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL5576920 0.82 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL6264346 0.81 TSHR (0.42) TSHRALDH1A1THRB
Ammonia Solution, Strong SCHEMBL7765025 0.81 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL3280963 0.81 TSHR (0.47) TSHRALDH1A1THRB
Hydrochloric Acid SCHEMBL23116685 0.81 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL7181452 0.79 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL28050153 0.79 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL556918 0.79 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL27552259 0.79 TSHR (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111107841-B Method for preparing solid dosage forms comprising antibodies by wet granulation, extrusion and spheronization 蒂洛特斯制药股份有限公司 2023-03-10 CN claimed