Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552498 | 0.85 | MEN1 (0.45) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL29132204 | 0.85 | MEN1 (0.45) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL21722177 | 0.83 | MEN1 (0.46) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL113614 | 0.76 | USP2 (0.54) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL31752290 | 0.76 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL1904787 | 0.76 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL31753756 | 0.76 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL15295758 | 0.75 | NR1H2 (0.54) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL28720772 | 0.74 | NR1H2 (0.43) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL28320681 | 0.74 | NR1H2 (0.43) | MEN1ALDH1A1MAPTKMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |