Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30137453 | 1.00 | PTPN11 (0.67) | PTPN11KCNH2 | |
| SCHEMBL31054029 | 0.91 | PTPN11 (0.68) | PTPN11KCNH2 | |
| Hydrochloric Acid SCHEMBL28967341 | 0.90 | PTPN11 (0.67) | PTPN11KCNH2 | |
| Hydrochloric Acid SCHEMBL30137515 | 0.90 | PTPN11 (0.67) | PTPN11KCNH2 | |
| SCHEMBL21233011 | 0.85 | PTPN11 (0.74) | PTPN11KCNH2 | |
| SCHEMBL30137509 | 0.84 | PTPN11 (0.61) | PTPN11KCNH2 | |
| SCHEMBL30137483 | 0.84 | PTPN11 (0.61) | PTPN11KCNH2 | |
| SCHEMBL28967361 | 0.84 | PTPN11 (0.61) | PTPN11KCNH2 | |
| SCHEMBL30137436 | 0.83 | PTPN11 (0.61) | PTPN11KCNH2 | |
| SCHEMBL28967348 | 0.83 | PTPN11 (0.72) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611869-A | Heterocyclic pyrazine derivative and application thereof in preparation of SHP2 inhibitor | 山东大学 | 2023-01-17 | — | — | CN | claimed |
| CN-115611869-A | Heterocyclic pyrazine derivative and application thereof in preparation of SHP2 inhibitor | 山东大学 | 2023-01-17 | — | — | CN | disclosed |