Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 18/20 | 0.84 |
| ▸ | RAF1 | P04049 | 8/20 | 0.76 |
| ▸ | KDR | P35968 | 2/20 | 0.71 |
| ▸ | FLT3 | P36888 | 2/20 | 0.68 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | LYN | P07948 | 1/20 | 0.64 |
| ▸ | RET | P07949 | 1/20 | 0.64 |
| ▸ | MET | P08581 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | BCR | P11274 | 1/20 | 0.64 |
| ▸ | FER | P16591 | 1/20 | 0.64 |
| ▸ | FLT1 | P17948 | 1/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418114 | 1.00 | BRAF (0.84) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL1012935 | 0.91 | BRAF (1.00) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL28967999 | 0.89 | KDR (0.90) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL30418040 | 0.89 | KDR (0.90) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL28967991 | 0.88 | BRAF (0.76) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL30418443 | 0.88 | BRAF (0.76) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL1012302 | 0.86 | BRAF (1.00) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL1011641 | 0.85 | BRAF (0.89) | BRAFRAF1KDRFLT3RIPK2 | |
| SCHEMBL1013128 | 0.83 | BRAF (1.00) | BRAFRAF1FLT3 | |
| SCHEMBL1012288 | 0.83 | BRAF (1.00) | BRAFRAF1KDRFLT3RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115778960-A | Application of heteroaromatic ring derivative in preparation of medicine for treating or preventing cachexia | 广州六顺生物科技有限公司 | 2023-03-14 | — | — | CN | disclosed |