⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050871 | 1.00 | — | — | |
| SCHEMBL289692 | 1.00 | — | — | |
| SCHEMBL895275 | 0.97 | — | — | |
| SCHEMBL186897 | 0.97 | — | — | |
| SCHEMBL1771875 | 0.94 | — | — | |
| SCHEMBL1771877 | 0.94 | — | — | |
| SCHEMBL3619266 | 0.94 | — | — | |
| SCHEMBL3265617 | 0.94 | — | — | |
| SCHEMBL31154658 | 0.94 | — | — | |
| SCHEMBL31252519 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389464-B2 | Arginase inhibitors as therapeutics | MARS, INCORPORATED (US) | 2022-07-19 | — | — | US | disclosed |
| US-11186802-B2 | Process for the decarboxylation, isomerization, hydrogenation, dehydrogenation and cyclization aromatization of fatty acids yielding products with significant aromatic content | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-11-30 | — | — | US | disclosed |
| US-20170183362-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED | 2017-06-29 | — | — | US | disclosed |
| EP-2852598-B1 | RING CONSTRAINED ANALOGS AS ARGINASE INHIBITORS | MARS INC (US) | 2016-05-11 | — | — | EP | disclosed |
| CN-104876955-A | Inhibitors Of Arginase And Their Therapeutic Applications | MARS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-104540836-A | Ring constrained analogs as arginase inhibitors | MARS INC | 2015-04-22 | — | — | CN | disclosed |
| EP-2852598-A1 | RING CONSTRAINED ANALOGS AS ARGINASE INHIBITORS | Mars, Incorporated (US) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013158262-A1 | RING CONSTRAINED ANALOGS AS ARGINASE INHIBITORS | MARS, INCORPORATED (US) | 2013-10-24 | — | — | WO | disclosed |
| EP-2205083-B1 | Substituted aryl sulfone derivatives as calcium channel blockers | MERCK SHARP & DOHME (US) | 2013-07-17 | — | — | EP | disclosed |
| CN-103068830-A | Arginase inhibitors and therapeutic uses thereof | MARS INC | 2013-04-24 | — | — | CN | disclosed |
| US-8304434-B2 | Substituted aryl sulfone derivatives as calcium channel blockers | MERCK SHARP & DOHME CORP. (US) | 2012-11-06 | — | — | US | disclosed |
| EP-1917221-B1 | SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF | UNIV YONSEI IACF (KR) | 2012-03-21 | — | — | EP | disclosed |
| EP-2427465-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20120041012-A1 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2012-02-16 | — | — | US | disclosed |
| WO-2011146324-A1 | SPIRO ISOXAZOLINE COMPOUNDS AS SSTR5 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-7947425-B2 | Fluorinated vinyl ethers, copolymers thereof, and use in lithographic photoresist compositions | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-20100210620-A1 | Substituted Aryl Sulfone Derivatives as Calcium Channel Blockers | SCHERING CORPORATION | 2010-08-19 | — | — | US | disclosed |
| WO-2010048138-A1 | SYNTHESIS OF INTERMEDIATES USEFUL FOR THE PRODUCTION OF CERTAIN CGRP INHIBITORS AND INTERMEDIATES USED IN SUCH SYNTHESIS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| CN-101528699-A | Heterocyclic cetp inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-09-09 | — | — | CN | disclosed |
| US-20060275701-A1 | Fluorinated vinyl ethers, copolymers thereof, and use in lithographic photoresist compositions | INTERNATIONAL BUSINESS MACHINES (US) | 2006-12-07 | — | — | US | disclosed |