Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24646024 | 1.00 | ACACB (0.45) | ACACBTRPV3ALDH1A1LMNAHPGD | |
| SCHEMBL30313723 | 1.00 | ACACB (0.45) | ACACBTRPV3ALDH1A1LMNAHPGD | |
| SCHEMBL28969194 | 1.00 | ACACB (0.45) | ACACBTRPV3ALDH1A1LMNAHPGD | |
| SCHEMBL13154794 | 0.85 | ACACB (0.46) | ACACBALDH1A1LMNAHPGDTSHR | |
| SCHEMBL30171098 | 0.85 | ACACB (0.46) | ACACBALDH1A1LMNAHPGDTSHR | |
| SCHEMBL28969181 | 0.82 | ACACB (0.44) | ACACBTRPV3ALDH1A1LMNAHPGD | |
| SCHEMBL24646682 | 0.79 | FFAR1 (0.41) | ACACBTRPV3GABRA5FFAR1GABRP | |
| SCHEMBL30313844 | 0.79 | FFAR1 (0.41) | ACACBTRPV3GABRA5FFAR1GABRP | |
| SCHEMBL24646681 | 0.79 | FFAR1 (0.41) | ACACBTRPV3GABRA5FFAR1GABRP | |
| SCHEMBL30211095 | 0.79 | FFAR1 (0.41) | ACACBTRPV3GABRA5FFAR1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867536-A | GPR40 agonists | 卡尔优普公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115667277-A | GPR40 agonists | 卡尔优普公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-4110760-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| EP-4110788-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |