Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25220782 | 0.89 | EGFR (0.49) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL26055501 | 0.86 | EGFR (0.51) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL25246042 | 0.85 | EGFR (0.48) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL25663596 | 0.83 | EGFR (0.47) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL25215929 | 0.83 | EGFR (0.53) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL25215331 | 0.80 | EPHA2 (0.45) | EGFRKDRAURKAPDGFRBTEK | |
| SCHEMBL25239983 | 0.78 | EGFR (0.49) | EGFRKDRERBB2 | |
| SCHEMBL25239984 | 0.78 | EGFR (0.49) | EGFRKDRERBB2 | |
| SCHEMBL25370288 | 0.77 | EGFR (0.48) | EGFRKDRERBB2 | |
| SCHEMBL25207968 | 0.77 | EGFR (0.48) | EGFRKDRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803325-A | EGFR inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-03-14 | — | — | CN | disclosed |