SCHEMBL28969412

SCHEMBL28969412

CCCCCCCCCCOC(=O)Nc1c(C)cccc1NC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
NLRP3 Q96P20 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP2C9 P11712 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28969408 1.00 MAPK1 (0.56) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL28969411 1.00 MAPK1 (0.56) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL28969407 1.00 MAPK1 (0.56) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL28969410 1.00 MAPK1 (0.56) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL28969406 0.99 MAPK1 (0.57) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL1025186 0.95 MAPK1 (0.59) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL28969405 0.95 MAPK1 (0.59) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL1023696 0.95 MAPK1 (0.59) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL1022068 0.95 MAPK1 (0.59) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19
SCHEMBL1023754 0.93 MAPK1 (0.60) MAPK1NLRP3SMN1; SMN2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024418-B Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source 河北工业大学 2023-01-24 CN claimed