Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15245773 | 0.87 | MAPT (0.58) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL4619581 | 0.84 | MEN1 (0.64) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL4619586 | 0.84 | MEN1 (0.64) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL12426701 | 0.82 | MAPT (0.79) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL2304778 | 0.82 | MAPT (0.79) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL2304774 | 0.82 | MAPT (0.79) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL4942494 | 0.81 | KMT2A (0.52) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL4942488 | 0.81 | KMT2A (0.52) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL6046338 | 0.79 | MAPT (0.57) | MAPTMEN1KMT2AKDM4EATM | |
| SCHEMBL6046337 | 0.79 | MAPT (0.57) | MAPTMEN1KMT2AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785079-A | 4- (1H-indole-5-yl) amino furan-2 (5H) -ketone compound and preparation and application thereof | 沈阳药科大学 | 2023-03-14 | — | — | CN | disclosed |