⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057330 | 0.84 | — | — | |
| SCHEMBL5927938 | 0.84 | — | — | |
| SCHEMBL1056632 | 0.81 | — | — | |
| SCHEMBL1059182 | 0.81 | — | — | |
| SCHEMBL1050892 | 0.80 | — | — | |
| SCHEMBL1059283 | 0.76 | — | — | |
| SCHEMBL1058243 | 0.74 | — | — | |
| SCHEMBL1058787 | 0.73 | — | — | |
| SCHEMBL1058823 | 0.73 | — | — | |
| SCHEMBL1081086 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982704-B1 | New molecular target of neurotoxicity | EXONHIT THERAPEUTICS SA (FR) | 2010-08-04 | — | — | EP | claimed |
| US-20090317842-A1 | Methods and Tools for The Therapy of Neurodegenerative Pathologies | EXONHIT THERAPEUTICS SA (FR) | 2009-12-24 | — | — | US | disclosed |
| EP-2047277-A2 | METHODS AND TOOLS FOR THE THERAPY OF NEURODEGENERATIVE PATHOLOGIES | Exonhit Therapeutics SA (FR) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008009868-A2 | METHODS AND TOOLS FOR THE THERAPY OF NEURODEGENERATIVE PATHOLOGIES | EXONHIT THERAPEUTICS SA (FR) | 2008-01-24 | — | — | WO | disclosed |
| EP-0180318-B1 | AMIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4745121-A | AMINE OR CARBOXAMIDE SUBSTITUTED | ICI AMERICAS INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0180318-A1 | Amide derivatives | ICI AMERICAS INC. (US) | 1986-05-07 | — | — | EP | disclosed |