SCHEMBL28972141

SCHEMBL28972141

CC(O)CN1CCN(c2ccc(Oc3cc(CN4CCC(OC(=O)N(C)C)CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28972127 0.91 FURIN (0.79) FURIN
SCHEMBL29928388 0.89 FURIN (0.83) FURIN
SCHEMBL21550747 0.89 FURIN (0.83) FURIN
SCHEMBL30387870 0.89 FURIN (0.63) FURIN
SCHEMBL21550750 0.89 FURIN (0.83) FURIN
SCHEMBL25180652 0.89 FURIN (0.63) FURIN
SCHEMBL28972140 0.89 FURIN (0.63) FURIN
SCHEMBL23364406 0.89 FURIN (0.69) FURIN
SCHEMBL27032456 0.87 FURIN (0.66) FURIN
SCHEMBL23364409 0.85 FURIN (0.68) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115666567-A Furin inhibitors for the treatment of coronavirus infection BP资产V股份有限公司 2023-01-31 — — CN claimed
Send feedback