SCHEMBL28973162

SCHEMBL28973162

CC1(C)C(=O)N(c2cnc(C#N)c(Cl)c2)C(=S)N1C1CCC(OCCOC2CCCCO2)CC1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 18/20 0.42
NR3C1 P04150 1/20 0.36
CHEK1 O14757 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338002 1.00 AR (0.42) ARNR3C1CHEK1
SCHEMBL28973160 1.00 AR (0.42) ARNR3C1CHEK1
SCHEMBL28973223 0.91 AR (0.48) ARNR3C1
SCHEMBL28973226 0.91 AR (0.48) ARNR3C1
SCHEMBL28973165 0.90 AR (0.33) AR
SCHEMBL30338710 0.90 AR (0.33) AR
SCHEMBL28973141 0.87 AR (0.44) AR
SCHEMBL28973139 0.87 AR (0.44) AR
SCHEMBL30390611 0.86 AR (0.44) ARNR3C1
SCHEMBL30338363 0.86 AR (0.44) ARNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115968293-A Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment 新基公司 2023-04-14 CN disclosed
CN-115955979-A Cereblan binding compounds, compositions thereof, and methods for treatment thereof 新基公司 2023-04-11 CN disclosed
CN-115835866-A Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment 新基公司 2023-03-21 CN disclosed