Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973973 | 0.90 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL9959090 | 0.88 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL21567650 | 0.86 | NR1H4 (0.77) | NR1H4 | |
| SCHEMBL21567860 | 0.86 | NR1H4 (0.90) | NR1H4 | |
| SCHEMBL19122003 | 0.85 | NR1H4 (0.80) | NR1H4 | |
| SCHEMBL9959168 | 0.85 | NR1H4 (0.94) | NR1H4 | |
| SCHEMBL30384758 | 0.83 | NR1H4 (0.83) | NR1H4 | |
| SCHEMBL28973986 | 0.83 | NR1H4 (0.83) | NR1H4 | |
| SCHEMBL17128561 | 0.82 | NR1H4 (0.82) | NR1H4 | |
| SCHEMBL9959364 | 0.82 | NR1H4 (0.82) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452235-B | Fluorine-containing isoxazole compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-02-17 | — | — | CN | disclosed |