Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.53 |
| ▸ | KDM5A | P29375 | 7/20 | 0.53 |
| ▸ | KDM5C | P41229 | 5/20 | 0.53 |
| ▸ | KDM4A | O75164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KDM6B | O15054 | 3/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ASPH | Q12797 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.53 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643176 | 0.90 | KDM4C (0.63) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL186166 | 0.90 | KDM4C (0.63) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25269346 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25224335 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25221271 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25258723 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25261764 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25229875 | 0.88 | KDM4C (0.67) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| SCHEMBL25263830 | 0.88 | KDM4C (0.61) | KDM4CKDM5BKDM5AKDM5CKDM4A | |
| Alcohol SCHEMBL28687926 | 0.80 | KDM5B (0.52) | KDM4CKDM5BKDM5AKDM5CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850349-A | Metal complex catalyst and application thereof in preparation of 1,2, 3-pentamethyl indane | 山东新和成药业有限公司 | 2023-03-28 | — | — | CN | disclosed |