Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23441985 | 0.95 | EGFR (0.71) | EGFR | |
| Trifluoroacetic Acid SCHEMBL23421545 | 0.94 | EGFR (0.73) | EGFR | |
| SCHEMBL23420836 | 0.93 | EGFR (0.68) | EGFR | |
| Trifluoroacetic Acid SCHEMBL28959681 | 0.92 | EGFR (0.57) | EGFR | |
| SCHEMBL25002657 | 0.92 | EGFR (0.72) | EGFR | |
| Trifluoroacetic Acid SCHEMBL28959662 | 0.90 | EGFR (0.60) | EGFR | |
| SCHEMBL29558989 | 0.90 | EGFR (0.73) | EGFR | |
| SCHEMBL22950935 | 0.90 | EGFR (0.73) | EGFR | |
| SCHEMBL22950947 | 0.90 | EGFR (0.64) | EGFR | |
| SCHEMBL22950985 | 0.89 | EGFR (0.80) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728932-A | Polyarylates as EGFR kinase inhibitors | 江苏先声药业有限公司 | 2022-07-08 | — | — | CN | disclosed |