Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974474 | 1.00 | HTT (0.49) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL30680300 | 1.00 | HTT (0.49) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL2995178 | 0.87 | SLC7A5 (0.56) | NAMPTSLC7A5AAK1NPC1RAB9A | |
| SCHEMBL2995175 | 0.87 | SLC7A5 (0.56) | NAMPTSLC7A5AAK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL23466585 | 0.85 | SLC7A5 (0.55) | NAMPTKMT2ASLC7A5MEN1AAK1 | |
| SCHEMBL23466413 | 0.85 | USP30 (0.54) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL23466415 | 0.85 | USP30 (0.54) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL30680277 | 0.85 | USP30 (0.54) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL23466769 | 0.83 | HTT (0.53) | HTTLMNANPSR1NAMPTKMT2A | |
| SCHEMBL23466770 | 0.83 | HTT (0.53) | HTTLMNANPSR1NAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |